HIDDEN CHEMICALS IN MEDICINES

As a physician specializing in Lifestyle Medicine and also personally affected by autoimmune conditions, I grapple with the idea of ingesting numerous extraneous ingredients daily, potentially for life. It's a concern that often goes overlooked in mainstream medical conversations, much to my bafflement and frustration. Many formulations of pressed pills, including generic levothyroxine, contain a plethora of inactive ingredients, some of which can raise serious concerns. 

One significant issue is the inclusion of artificial dyes like red and yellow dyes in certain pill formulations. As a healthcare provider and someone managing this condition firsthand, I find it alarming that such unnecessary additives find their way into medications crucial for managing thyroid health. These additives serve no therapeutic purpose and may pose risks for individuals sensitive or allergic to these compounds. 

Hypothyroidism is a condition that affects millions of people worldwide. It occurs when the thyroid gland, located in the neck, does not produce enough thyroid hormone to meet the body's needs. Thyroid hormones play a crucial role in regulating metabolism, energy levels, body temperature, and heart rate. When levels are low, as in hypothyroidism, it can lead to a range of symptoms such as fatigue, weight gain, cold sensitivity, and hair loss. 

One of the most common medications prescribed for hypothyroidism is levothyroxine. This synthetic thyroid hormone is designed to replace the missing hormone in the body, helping to alleviate symptoms and restore normal thyroid function. Levothyroxine is typically taken orally in the form of pressed pills, which contain both active and inactive ingredients. 

When it comes to understanding what we put into our bodies, it's essential to know not only the active ingredients but also the inactive ingredients in medications. In the case of levothyroxine, both generic versions and brand names like Synthroid are widely used. However, finding detailed information about the inactive ingredients can be surprisingly challenging, even on official pharmaceutical websites. 

Let's delve into the ingredients commonly found in pressed pills of levothyroxine, using both generic and brand name examples. 

### Inactive Ingredients in Generic Levothyroxine: 

1. Microcrystalline Cellulose: Often used as a binder or filler in medications, microcrystalline cellulose helps maintain the pill's structure and aids in its absorption. 

2. Calcium Phosphate: This compound serves as a buffering agent to maintain the pill's stability and pH balance, ensuring the active ingredient remains effective. 

3. Colloidal Silicon Dioxide: Also known as silica, this ingredient prevents clumping of the powder during pill formation and helps with disintegration upon ingestion. 

4. Magnesium Stearate: Used as a lubricant in pill manufacturing, magnesium stearate ensures the ingredients flow smoothly through machinery and do not stick to each other. 

5. Sodium Starch Glycolate: This ingredient assists in the rapid disintegration of the pill in the digestive tract, ensuring timely absorption of the active ingredient. 

### Inactive Ingredients in Synthroid: 

While specific inactive ingredients in brand name medications like Synthroid may vary slightly, they generally include similar compounds to those found in generic levothyroxine. However, due to proprietary formulations, exact details may not always be readily available to consumers. 

Synthroid's inactive ingredients may include: 

1. Acacia

2. Confectioner's Sugar

3. Lactose Monohydrate

4. Magnesium Stearate

5. Povidone

6. Talc

**It's important to note that inactive ingredients can vary between manufacturers and different formulations of the same medication. Individuals with allergies or sensitivities to certain compounds should consult their healthcare providers or pharmacists to ensure the medication they are taking is suitable for them. 

So, Now What?!

Personally, I advocate for and use Tirosint, a medication with a cleaner ingredient profile, devoid of artificial dyes and unnecessary fillers commonly found in pressed pills. I often recommend Tirosint to my patients, prioritizing its use despite potential out-of-pocket costs. The rationale is simple yet profound: prioritizing health over convenience or cost-cutting measures. 

However, the battle doesn't end there. Insurance coverage often becomes a significant hurdle in accessing medications like Tirosint. I've had countless encounters with insurance companies where they insist on generic alternatives, completely disregarding the extensive lists of inactive ingredients that can be problematic for sensitive individuals. This puts patients in a difficult position, where their optimal health outcomes are compromised due to bureaucratic rigidity. 

My advocacy extends beyond the clinic walls; I've engaged in relentless discussions and appeals with insurance providers to secure coverage for Tirosint on behalf of my patients. It's a battle fought not just for individual cases but to highlight the broader issue of ingredient transparency and patient-centered care in medication access. 

In conclusion, the conversation about medication ingredients shouldn't be relegated to the sidelines. As healthcare providers, we owe it to our patients to consider not just the active compounds but also the inactive ingredients that can impact overall health and well-being. Prioritizing cleaner formulations like Tirosint, despite challenges, underscores our commitment to patient-centered care and optimal health outcomes.

IF YOU WOULD LIKE TO READ MORE ON MEDICAL TOPICS, PLEASE CLICK TO NAVIGATE TO MY BLOG AT BEEHIIV:   AND OF COURSE, SHOOT ME A MESSAGE IF YOU HAVE A TOPIC OR QUESTION YOU'D LIKE ME TO COVER!

Dana Mincer, DO
Love Health DPC
Fort Washington, PA